Psoriasis is a chronic condition with periods of remission and flares. Identifying and managing your personal triggers is one of the most powerful tools you have for reducing flare frequency and severity.
Stress
Stress is one of the most consistently reported psoriasis triggers. The biological mechanism is well-understood: stress activates the hypothalamic-pituitary-adrenal (HPA) axis and sympathetic nervous system, releasing hormones that directly influence immune signaling.
Management: Regular exercise, mindfulness practice, adequate sleep, and counseling have all been shown to reduce stress-related flares.
Infections
Streptococcal throat infections (strep throat) are a well-established trigger for guttate psoriasis, small, drop-shaped plaques, and can worsen plaque psoriasis. Treating infections promptly can help prevent flares.
Skin Injury (Koebner Phenomenon)
New psoriasis plaques can develop at the site of skin injuries, cuts, sunburns, scratches, insect bites, or even surgery. This is called the Koebner phenomenon. Protecting the skin from unnecessary trauma can reduce new plaque development.
Medications
Several common medications can trigger or worsen psoriasis, including beta-blockers, ACE inhibitors, lithium, antimalarial drugs, and oral corticosteroids (when withdrawn). Always tell your physician about your psoriasis before starting new medications.
Alcohol and Smoking
Heavy alcohol consumption and smoking are associated with both worsening psoriasis severity and reduced treatment response. Reducing or eliminating both can meaningfully improve disease control.
Cold and Dry Weather
Dry air strips moisture from the skin and can worsen plaque formation. Using a humidifier and applying heavy emollients during winter can help.
Clinical Trials for Psoriasis
If flare management is not providing sufficient control, a clinical trial may offer access to newer treatments. View our psoriasis study at NuLine in Oakland Park.